Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutant frequencies. [electronic resource]
Producer: 20021002Description: 9253-9 p. digitalISSN:- 0022-538X
- Animals
- Anti-HIV Agents -- pharmacology
- COS Cells
- Dose-Response Relationship, Drug
- Drug Resistance, Viral -- genetics
- Genetic Vectors
- HIV Reverse Transcriptase -- metabolism
- HIV-1 -- drug effects
- HeLa Cells
- Humans
- Hydroxyurea -- pharmacology
- Lamivudine -- pharmacology
- Mutation
- Reverse Transcriptase Inhibitors -- pharmacology
- Thymidine -- pharmacology
- Virus Replication
- Zidovudine -- pharmacology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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