Costimulation of Gi- and G12/G13-mediated signaling pathways induces integrin alpha IIbbeta 3 activation in platelets. [electronic resource]
Producer: 20021219Description: 39493-8 p. digitalISSN:- 0021-9258
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid -- pharmacology
- Adenosine Diphosphate -- metabolism
- Adenosine Triphosphate -- metabolism
- Animals
- Blood Platelets -- metabolism
- Collagen -- metabolism
- DNA-Binding Proteins -- metabolism
- Dose-Response Relationship, Drug
- Fibrinogen -- metabolism
- GTP-Binding Protein alpha Subunits, G12-G13
- GTP-Binding Protein alpha Subunits, Gi-Go -- metabolism
- Heterotrimeric GTP-Binding Proteins -- metabolism
- Intracellular Signaling Peptides and Proteins
- Mice
- Mice, Transgenic
- Platelet Activation
- Platelet Glycoprotein GPIIb-IIIa Complex -- metabolism
- Protein Binding
- Protein Serine-Threonine Kinases -- metabolism
- Signal Transduction
- Thrombin -- pharmacology
- Thromboxane A2 -- pharmacology
- rho-Associated Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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