Heterologous desensitization of opioid receptors by chemokines inhibits chemotaxis and enhances the perception of pain. [electronic resource]
Producer: 20020923Description: 10276-81 p. digitalISSN:- 0027-8424
- Analgesics, Opioid -- pharmacology
- Animals
- Cell Line
- Cells, Cultured
- Chemokine CCL19
- Chemokine CXCL12
- Chemokines -- metabolism
- Chemokines, CC -- pharmacology
- Chemokines, CXC -- pharmacology
- Chemotaxis -- drug effects
- Enkephalin, D-Penicillamine (2,5)- -- pharmacology
- Humans
- Interleukin-8 -- pharmacology
- Mice
- Monocytes -- cytology
- Pain -- physiopathology
- Receptors, CCR2
- Receptors, CCR5 -- metabolism
- Receptors, CCR7
- Receptors, CXCR4 -- metabolism
- Receptors, Chemokine -- metabolism
- Receptors, Opioid, delta -- metabolism
- Receptors, Opioid, mu -- metabolism
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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