Cyclic AMP-dependent transcriptional up-regulation of phosphodiesterase 4D5 in human airway smooth muscle cells. Identification and characterization of a novel PDE4D5 promoter. [electronic resource]
Producer: 20021113Description: 35980-9 p. digitalISSN:- 0021-9258
- 3',5'-Cyclic-AMP Phosphodiesterases -- metabolism
- 8-Bromo Cyclic Adenosine Monophosphate -- metabolism
- Alternative Splicing
- Animals
- Base Sequence
- CHO Cells
- Chromosomes, Human, Pair 5
- Cricetinae
- Culture Media, Serum-Free -- pharmacology
- Cyclic AMP -- metabolism
- Cyclic Nucleotide Phosphodiesterases, Type 3
- Cyclic Nucleotide Phosphodiesterases, Type 4
- Down-Regulation
- Genes, Reporter
- Humans
- Kinetics
- Luciferases -- metabolism
- Models, Genetic
- Molecular Sequence Data
- Muscle, Smooth -- cytology
- Mutagenesis, Site-Directed
- Phosphoric Diester Hydrolases -- biosynthesis
- Precipitin Tests
- Promoter Regions, Genetic
- Protein Isoforms
- Protein Structure, Tertiary
- Reverse Transcriptase Polymerase Chain Reaction
- Trachea -- cytology
- Transcription, Genetic
- Transfection
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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