Aberrant methylation of the CDKN2a/p16INK4a gene promoter region in preinvasive bronchial lesions: a prospective study in high-risk patients without invasive cancer. [electronic resource]
Producer: 20020808Description: 189-93 p. digitalISSN:- 0020-7136
- Asbestos -- adverse effects
- Biopsy
- Cyclin-Dependent Kinase Inhibitor p16 -- genetics
- DNA Methylation
- DNA, Neoplasm -- genetics
- Disease Progression
- Epithelial Cells -- metabolism
- Follow-Up Studies
- Gene Expression Regulation, Neoplastic
- Humans
- Lung Neoplasms -- etiology
- Metaplasia -- genetics
- Middle Aged
- Precancerous Conditions -- genetics
- Promoter Regions, Genetic
- Prospective Studies
- Risk Factors
- Smoking -- adverse effects
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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