RPR-115135, a farnesyltransferase inhibitor, increases 5-FU- cytotoxicity in ten human colon cancer cell lines: role of p53. [electronic resource]
Producer: 20020730Description: 266-75 p. digitalISSN:- 0020-7136
- Alkyl and Aryl Transferases -- antagonists & inhibitors
- Antimetabolites, Antineoplastic -- pharmacology
- Cell Cycle -- drug effects
- Colonic Neoplasms -- drug therapy
- Enzyme Inhibitors -- pharmacology
- Farnesyltranstransferase
- Fluorouracil -- pharmacology
- Humans
- Indoles -- pharmacology
- Tumor Cells, Cultured
- Tumor Suppressor Protein p14ARF -- genetics
- Tumor Suppressor Protein p53 -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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