A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration. [electronic resource]
Producer: 20020722Description: 905-19 p. digitalISSN:- 0896-6273
- Animals
- Ataxin-1
- Ataxins
- Disease Models, Animal
- Female
- Humans
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Neurologic Mutants
- Nerve Tissue Proteins -- biosynthesis
- Neurodegenerative Diseases -- genetics
- Nuclear Proteins -- biosynthesis
- Purkinje Cells -- metabolism
- Solubility
- Spinocerebellar Ataxias -- genetics
- Trinucleotide Repeats -- genetics
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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