Channel openings are necessary but not sufficient for use-dependent block of cardiac Na(+) channels by flecainide: evidence from the analysis of disease-linked mutations. [electronic resource]
Producer: 20021204Description: 39-51 p. digitalISSN:- 0022-1295
- Anti-Arrhythmia Agents -- pharmacology
- Arrhythmias, Cardiac -- genetics
- Cell Line
- Flecainide -- pharmacology
- Humans
- Long QT Syndrome -- genetics
- Mutation -- physiology
- Myocardium -- metabolism
- NAV1.5 Voltage-Gated Sodium Channel
- Sodium Channel Blockers -- pharmacology
- Sodium Channels -- drug effects
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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