Efficient isolation of novel human monoclonal antibodies with neutralizing activity against HIV-1 from transgenic mice expressing human Ig loci. [electronic resource]
Producer: 20020813Description: 595-605 p. digitalISSN:- 0022-1767
- Amino Acid Sequence
- Animals
- Anti-HIV Agents -- chemistry
- Antibodies, Heterophile -- chemistry
- Antibodies, Monoclonal -- biosynthesis
- Antibody Specificity -- genetics
- Binding, Competitive -- genetics
- Conserved Sequence -- immunology
- Epitope Mapping
- Epitopes -- chemistry
- Gene Expression Regulation -- immunology
- Genes, Immunoglobulin
- Genetic Markers -- immunology
- HIV Antibodies -- biosynthesis
- HIV Envelope Protein gp120 -- immunology
- HIV-1 -- immunology
- Humans
- Hybridomas
- Immunoglobulin Variable Region -- chemistry
- Mice
- Mice, Transgenic
- Molecular Sequence Data
- Neutralization Tests -- methods
- Protein Structure, Tertiary -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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