Tirofiban blocks platelet adhesion to fibrin with minimal perturbation of GpIIb/IIIa structure. [electronic resource]
Producer: 20020909Description: 910-7 p. digitalISSN:- 0340-6245
- Adult
- Circular Dichroism
- Dose-Response Relationship, Drug
- Fibrin -- metabolism
- Humans
- Microscopy, Electron
- Nephelometry and Turbidimetry
- Platelet Adhesiveness -- drug effects
- Platelet Aggregation Inhibitors -- administration & dosage
- Platelet Glycoprotein GPIIb-IIIa Complex -- chemistry
- Protein Conformation -- drug effects
- Protein Interaction Mapping
- Protein Structure, Secondary -- drug effects
- Protein Structure, Tertiary -- drug effects
- Protein Subunits
- Receptor Aggregation -- drug effects
- Tirofiban
- Tyrosine -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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