Glucose desensitization in INS-1 cells: evidence of impaired function caused by glucose metabolite(s) rather than by the glucose molecule per se. [electronic resource]
Producer: 20020718Description: 671-7 p. digitalISSN:- 0026-0495
- Animals
- Cell Line
- Deoxyglucose -- pharmacology
- Dose-Response Relationship, Drug
- Drug Tolerance -- physiology
- Enzyme Inhibitors -- pharmacology
- Glucokinase -- antagonists & inhibitors
- Glucose -- metabolism
- Glucose-6-Phosphate Isomerase -- antagonists & inhibitors
- Glyceraldehyde -- pharmacology
- Insulin -- genetics
- Insulin Secretion
- Intracellular Fluid -- metabolism
- Islets of Langerhans -- drug effects
- Mannoheptulose -- pharmacology
- RNA, Messenger -- metabolism
- Rats
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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