Autocrine human growth hormone inhibits placental transforming growth factor-beta gene transcription to prevent apoptosis and allow cell cycle progression of human mammary carcinoma cells. [electronic resource]
Producer: 20020906Description: 26662-72 p. digitalISSN:- 0021-9258
- Apoptosis -- drug effects
- Binding Sites
- Blotting, Northern
- Breast Neoplasms -- pathology
- Cell Cycle -- drug effects
- Cyclin D1 -- biosynthesis
- Female
- Genes, Reporter
- Growth Substances -- genetics
- Human Growth Hormone -- pharmacology
- Humans
- Insulin-Like Growth Factor I -- metabolism
- Luciferases -- metabolism
- Oligonucleotides, Antisense -- metabolism
- Plasmids
- Pregnancy Proteins -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Transcription, Genetic -- drug effects
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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