Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation. [electronic resource]
Producer: 20020522Description: 417-27 p. digitalISSN:- 0021-9525
- Cell Cycle
- Cysteine Endopeptidases -- metabolism
- Green Fluorescent Proteins
- HeLa Cells
- Humans
- Luminescent Proteins -- genetics
- Lysine -- metabolism
- Multienzyme Complexes -- antagonists & inhibitors
- Mutation
- Neurodegenerative Diseases -- enzymology
- Neurons -- metabolism
- Proteasome Endopeptidase Complex
- Proteins -- metabolism
- Substrate Specificity
- Tumor Cells, Cultured
- Ubiquitin -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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