Synthesis and biological evaluation of structurally highly modified analogues of the antimitotic natural product curacin A. [electronic resource]
Producer: 20020510Description: 1901-17 p. digitalISSN:- 0022-2623
- Antineoplastic Agents -- chemical synthesis
- Biopolymers
- Blood Proteins -- metabolism
- Cell Division -- drug effects
- Cyclopropanes -- chemistry
- Drug Screening Assays, Antitumor
- Humans
- Oximes -- chemical synthesis
- Protein Binding
- Stereoisomerism
- Structure-Activity Relationship
- Thiazoles -- chemistry
- Thiophenes -- chemical synthesis
- Tubulin -- chemistry
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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