Prolonged culture of HOS 58 human osteosarcoma cells with 1,25-(OH)2-D3, TGF-beta, and dexamethasone reveals physiological regulation of alkaline phosphatase, dissociated osteocalcin gene expression, and protein synthesis and lack of mineralization. [electronic resource]
Producer: 20020722Description: 279-94 p. digitalISSN:- 0730-2312
- Adult
- Alkaline Phosphatase -- genetics
- Animals
- Blotting, Northern
- Calcification, Physiologic
- Calcitriol -- pharmacology
- Collagen Type I -- genetics
- Core Binding Factor alpha Subunits
- DNA Primers -- chemistry
- DNA-Binding Proteins -- metabolism
- Dexamethasone -- pharmacology
- Gene Expression
- Gene Expression Regulation, Enzymologic
- Humans
- Male
- Mice
- Microscopy, Electron, Scanning
- Osteocalcin -- genetics
- Osteosarcoma -- drug therapy
- RNA, Messenger -- metabolism
- Rats
- Reverse Transcriptase Polymerase Chain Reaction
- Transcription Factors -- metabolism
- Transforming Growth Factor beta -- pharmacology
- Tumor Cells, Cultured -- drug effects
No physical items for this record
Publication Type: Comparative Study; Journal Article
There are no comments on this title.
Log in to your account to post a comment.