Detection of radiation and cyclophosphamide-induced mutations in individual mouse sperm at a human expanded trinucleotide repeat locus transgene. [electronic resource]
Producer: 20020612Description: 121-38 p. digitalISSN:- 0027-5107
- Animals
- Antineoplastic Agents, Alkylating -- toxicity
- Blotting, Southern
- Cyclophosphamide -- toxicity
- DNA Mutational Analysis
- DNA Primers
- Humans
- Male
- Mice
- Mice, Transgenic
- Mutation -- drug effects
- Myotonic Dystrophy -- genetics
- Myotonin-Protein Kinase
- Polymerase Chain Reaction
- Protein Serine-Threonine Kinases
- Proteins -- genetics
- Spermatozoa -- drug effects
- Trinucleotide Repeat Expansion -- genetics
- Whole-Body Irradiation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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