Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways. [electronic resource]
Producer: 20020617Description: 2637-46 p. digitalISSN:- 0006-4971
- DNA-Binding Proteins -- chemistry
- Dimerization
- Drug Interactions
- Drug Resistance
- Humans
- Leukemia, Promyelocytic, Acute -- etiology
- Milk Proteins
- Nuclear Receptor Co-Repressor 2
- Nuclear Receptor Coactivator 3
- Oncogene Proteins, Fusion -- chemistry
- Protein Structure, Tertiary
- Receptors, Retinoic Acid -- genetics
- Repressor Proteins -- drug effects
- Response Elements
- Retinoic Acid Receptor alpha
- Retinoid X Receptors
- STAT3 Transcription Factor
- STAT5 Transcription Factor
- Signal Transduction
- Trans-Activators -- chemistry
- Transcription Factors -- drug effects
- Transcription, Genetic -- drug effects
- Transfection
- Tretinoin -- pharmacology
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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