Overexpression of pyrimidine nucleoside phosphorylase enhances the sensitivity to 5'-deoxy-5-fluorouridine in tumour cells in vitro and in vivo. [electronic resource]
Producer: 20020517Description: 712-7 p. digitalISSN:- 0959-8049
- Adenocarcinoma -- drug therapy
- Animals
- Antimetabolites, Antineoplastic -- pharmacology
- Cell Survival -- drug effects
- Colonic Neoplasms -- drug therapy
- Combined Modality Therapy
- DNA, Complementary -- genetics
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Female
- Floxuridine -- pharmacology
- Fluorouracil -- pharmacology
- Genetic Therapy -- methods
- Humans
- Mice
- Mice, Inbred BALB C
- Neoplasm Transplantation
- Pentosyltransferases -- biosynthesis
- Prodrugs -- pharmacology
- Pyrimidine Phosphorylases
- Transfection
- Tumor Cells, Cultured
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Publication Type: Journal Article
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