Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins. [electronic resource]
Producer: 20020719Description: 22768-80 p. digitalISSN:- 0021-9258
- Age Factors
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Behavior, Animal
- Fear
- Hippocampus -- metabolism
- Immunoblotting
- Immunohistochemistry
- Learning
- Membrane Proteins -- genetics
- Mice
- Mice, Transgenic
- Mutation
- Presenilin-1
- Protein Binding
- Receptors, Nicotinic -- metabolism
- Shock
- Time Factors
- Transgenes
- Up-Regulation
- alpha7 Nicotinic Acetylcholine Receptor
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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