Hydroxyethylamine isostere of an HIV-1 protease inhibitor prefers its amine to the hydroxy group in binding to catalytic aspartates. A synchrotron study of HIV-1 protease in complex with a peptidomimetic inhibitor. [electronic resource]
Producer: 20020429Description: 1432-8 p. digitalISSN:- 0022-2623
- Amines -- chemistry
- Amino Acids -- chemistry
- Aspartic Acid -- chemistry
- Binding Sites
- Catalysis
- Dimerization
- Endopeptidases -- chemistry
- Ethanolamines -- chemistry
- Glycerol -- chemistry
- HIV Protease -- metabolism
- HIV Protease Inhibitors -- chemistry
- Hydrogen Bonding
- Kinetics
- Models, Chemical
- Models, Molecular
- Oxygen -- chemistry
- Peptide Fragments
- Protein Binding
- Protein Conformation
- Synchrotrons
- X-Ray Diffraction
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.