Design of a targeted peptide nucleic acid prodrug to inhibit hepatic human microsomal triglyceride transfer protein expression in hepatocytes. [electronic resource]
Producer: 20020723Description: 295-302 p. digitalISSN:- 1043-1802
- Animals
- Asialoglycoproteins -- pharmacology
- Base Sequence
- Biological Transport -- drug effects
- Carrier Proteins -- genetics
- Cells, Cultured
- Drug Delivery Systems
- Drug Design
- Fetuins
- Gene Expression Regulation -- drug effects
- Hepatocytes -- drug effects
- Humans
- Kinetics
- Mice
- Mice, Inbred C57BL
- Microsomes, Liver -- drug effects
- Molecular Structure
- Peptide Nucleic Acids -- chemical synthesis
- Prodrugs -- chemical synthesis
- RNA, Messenger -- genetics
- Tumor Cells, Cultured
- alpha-Fetoproteins -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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