Vanadate trapping of nucleotide at the ATP-binding sites of human multidrug resistance P-glycoprotein exposes different residues to the drug-binding site. [electronic resource]
Producer: 20020424Description: 3511-6 p. digitalISSN:- 0027-8424
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- chemistry
- Adenosine Triphosphate -- metabolism
- Adenylyl Imidodiphosphate -- metabolism
- Binding Sites
- Biological Transport
- Catalysis
- Cell Membrane -- metabolism
- Cross-Linking Reagents -- metabolism
- Cysteine -- genetics
- Disulfides -- metabolism
- Drug Resistance, Multiple
- Humans
- Models, Biological
- Mutation
- Phenanthrolines -- metabolism
- Protein Conformation
- Vanadates -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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