The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c. [electronic resource]
Producer: 20020613Description: 16547-52 p. digitalISSN:- 0021-9258
- Androstadienes -- pharmacology
- Animals
- Apoptosis
- Blotting, Western
- Cell Line
- Cell Survival
- Cells, Cultured
- Chloride Channels -- antagonists & inhibitors
- Cycloheximide -- pharmacology
- Cytochrome c Group -- metabolism
- Cytosol -- metabolism
- DNA Damage
- Diuretics -- pharmacology
- Enzyme Inhibitors -- pharmacology
- Etoposide -- pharmacology
- Fibroblasts -- drug effects
- Furosemide -- pharmacology
- Mice
- Mitochondria -- metabolism
- Nucleic Acid Synthesis Inhibitors -- pharmacology
- Phosphorylation
- Protein Synthesis Inhibitors -- pharmacology
- Protein Transport
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Proto-Oncogene Proteins c-myc -- metabolism
- Time Factors
- Transfection
- Tumor Suppressor Protein p53 -- metabolism
- Ubiquinone -- analogs & derivatives
- Up-Regulation
- Wortmannin
- bcl-2-Associated X Protein
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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