Early expression of myocardial HIF-1alpha in response to mechanical stresses: regulation by stretch-activated channels and the phosphatidylinositol 3-kinase signaling pathway. [electronic resource]
Producer: 20020221Description: E25-33 p. digitalISSN:- 1524-4571
- Androstadienes -- pharmacology
- Animals
- Cell Nucleus -- metabolism
- Endothelial Growth Factors -- genetics
- Enzyme Inhibitors -- pharmacology
- Gadolinium -- pharmacology
- Gene Expression Regulation -- drug effects
- Hypoxia-Inducible Factor 1, alpha Subunit
- In Vitro Techniques
- Ion Channels -- metabolism
- Lymphokines -- genetics
- Male
- Myocardial Ischemia -- metabolism
- Myocardium -- cytology
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Phosphorylation -- drug effects
- Protein Serine-Threonine Kinases
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-akt
- RNA, Messenger -- metabolism
- Rats
- Rats, Sprague-Dawley
- Signal Transduction -- drug effects
- Sirolimus -- pharmacology
- Specific Pathogen-Free Organisms
- Stress, Mechanical
- Transcription Factors -- biosynthesis
- Vascular Endothelial Growth Factor A
- Vascular Endothelial Growth Factors
- Ventricular Function, Left -- physiology
- Wortmannin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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