Role of CYP3A4 and CYP2C19 in the stereoselective metabolism of lansoprazole by human liver microsomes. [electronic resource]
Producer: 20020723Description: 709-15 p. digitalISSN:- 0031-6970
- 2-Pyridinylmethylsulfinylbenzimidazoles
- Aryl Hydrocarbon Hydroxylases
- Biotransformation
- Cytochrome P-450 CYP2C19
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- physiology
- Enzyme Inhibitors -- metabolism
- Humans
- Hydroxylation
- In Vitro Techniques
- Lansoprazole
- Microsomes, Liver -- metabolism
- Mixed Function Oxygenases -- physiology
- Omeprazole -- analogs & derivatives
- Protein Isoforms
- Proton Pump Inhibitors
- Stereoisomerism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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