Missense mutations in the beta(3) subunit have a different impact on the expression and function between alpha(IIb)beta(3) and alpha(v)beta(3). [electronic resource]
Producer: 20020306Description: 931-8 p. digitalISSN:- 0006-4971
- Adult
- Amino Acid Sequence
- Antigens, CD -- biosynthesis
- Blood Platelets -- chemistry
- Cell Line
- DNA Mutational Analysis
- Female
- Fibrinogen -- metabolism
- Gene Expression
- Humans
- Integrin beta3
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation, Missense -- genetics
- Platelet Glycoprotein GPIIb-IIIa Complex -- genetics
- Platelet Membrane Glycoproteins -- biosynthesis
- Protein Binding
- Receptors, Vitronectin -- genetics
- Thrombasthenia -- blood
- Transfection
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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