Adenovirus-directed expression of Q227L-G alpha(s) inhibits growth of established tumors of later-stage human breast cancer cells in athymic mice. [electronic resource]
Producer: 20020307Description: 1671-6 p. digitalISSN:- 0027-8424
- 8-Bromo Cyclic Adenosine Monophosphate -- pharmacology
- Adenoviridae -- genetics
- Amino Acid Substitution
- Animals
- Breast Neoplasms -- pathology
- Cell Cycle Proteins -- genetics
- Cell Division -- drug effects
- Cyclin-Dependent Kinase Inhibitor p27
- Epidermal Growth Factor -- pharmacology
- Female
- GTP Phosphohydrolases -- genetics
- GTP-Binding Protein alpha Subunits, Gs -- chemistry
- Genes, Tumor Suppressor -- drug effects
- Heterotrimeric GTP-Binding Proteins -- chemistry
- Humans
- MAP Kinase Signaling System -- drug effects
- Mice
- Mice, Nude
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3
- Mitogen-Activated Protein Kinases -- metabolism
- Recombinant Proteins -- chemistry
- Transfection
- Transplantation, Heterologous
- Tumor Cells, Cultured
- Tumor Suppressor Proteins -- genetics
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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