S2' substrate specificity and the role of His110 and His111 in the exopeptidase activity of human cathepsin B. [electronic resource]
Producer: 20020312Description: 613-9 p. digitalISSN:- 0264-6021
- Amidohydrolases -- metabolism
- Aspartic Acid -- chemistry
- Binding Sites
- Cathepsin B -- chemistry
- Exopeptidases -- metabolism
- Glutamic Acid -- chemistry
- Histidine -- chemistry
- Humans
- Ions
- Kinetics
- Lysosomes -- enzymology
- Models, Molecular
- Mutagenesis, Site-Directed
- Mutation
- Protein Binding
- Protein Structure, Tertiary
- Recombinant Proteins -- metabolism
- Substrate Specificity
- Tolbutamide -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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