Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein. [electronic resource]
Producer: 20020510Description: 11345-51 p. digitalISSN:- 0021-9258
- Apoptosis -- physiology
- Apoptosis Regulatory Proteins
- Carrier Proteins -- metabolism
- Genetic Linkage
- Humans
- Intracellular Signaling Peptides and Proteins
- Jurkat Cells
- Mitochondria -- metabolism
- Mitochondrial Proteins -- metabolism
- Proteins -- antagonists & inhibitors
- Proto-Oncogene Proteins c-bcl-2 -- physiology
- X-Linked Inhibitor of Apoptosis Protein
- bcl-X Protein
- fas Receptor -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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