Contrasting, species-dependent modulation of copper-mediated neurotoxicity by the Alzheimer's disease amyloid precursor protein. [electronic resource]
Producer: 20020130Description: 365-76 p. digitalISSN:- 1529-2401
- Alzheimer Disease -- metabolism
- Amyloid beta-Protein Precursor -- chemistry
- Animals
- Binding Sites -- genetics
- Caenorhabditis elegans
- Cells, Cultured
- Conserved Sequence -- genetics
- Copper -- toxicity
- Drosophila
- Glycine -- chemistry
- Humans
- Lipid Peroxidation -- drug effects
- Lipoproteins, LDL -- drug effects
- Mice
- Mutagenesis, Site-Directed
- Neurons -- cytology
- Organometallic Compounds -- chemistry
- Oxidation-Reduction -- drug effects
- Peptide Fragments -- chemistry
- Protein Structure, Tertiary -- genetics
- Recombinant Proteins -- chemistry
- Sequence Homology, Amino Acid
- Species Specificity
- Structure-Activity Relationship
- Takifugu
- Xenopus
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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