Role of cytochrome P450 isoenzymes in metabolism of O(6)-benzylguanine: implications for dacarbazine activation. [electronic resource]
Producer: 20020327Description: 4239-44 p. digitalISSN:- 1078-0432
- Antineoplastic Agents -- pharmacokinetics
- Biotransformation
- Carmustine -- pharmacokinetics
- Cytochrome P-450 Enzyme System -- metabolism
- Cytosol -- enzymology
- DNA Repair -- physiology
- Dacarbazine -- analogs & derivatives
- Guanine -- analogs & derivatives
- Humans
- Isoenzymes -- metabolism
- Kinetics
- Liver -- enzymology
- Microsomes, Liver -- enzymology
- Temozolomide
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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