Relation between the flexibility of the WPD loop and the activity of the catalytic domain of protein tyrosine phosphatase SHP-1. [electronic resource]
Producer: 20020313Description: 47-55 p. digitalISSN:- 0730-2312
- Alanine
- Catalytic Domain -- physiology
- Conserved Sequence -- genetics
- Enzyme Activation
- Intracellular Signaling Peptides and Proteins
- Kinetics
- Models, Molecular
- Mutation
- Pliability
- Proline
- Protein Conformation
- Protein Structure, Secondary
- Protein Tyrosine Phosphatase, Non-Receptor Type 11
- Protein Tyrosine Phosphatase, Non-Receptor Type 6
- Protein Tyrosine Phosphatases -- chemistry
- Sequence Homology, Amino Acid
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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