Reduced phospholipase C-beta activity and isoform expression in the cerebellum of TS65Dn mouse: a model of Down syndrome. [electronic resource]
Producer: 20020124Description: 540-50 p. digitalISSN:- 0360-4012
- Animals
- Calcium -- metabolism
- Cell Membrane -- drug effects
- Cerebellum -- drug effects
- Cerebral Cortex -- enzymology
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Down Syndrome -- enzymology
- Down-Regulation -- drug effects
- GTP-Binding Proteins -- drug effects
- Gene Expression Regulation, Enzymologic -- drug effects
- Guanosine 5'-O-(3-Thiotriphosphate) -- pharmacokinetics
- Isoenzymes -- deficiency
- Male
- Mice
- Mice, Neurologic Mutants
- Muscarinic Agonists -- pharmacology
- Muscarinic Antagonists -- pharmacology
- Phosphatidylinositol 4,5-Diphosphate -- genetics
- Phospholipase C beta
- Protein Isoforms -- deficiency
- Receptor, Serotonin, 5-HT2A
- Receptors, Muscarinic -- drug effects
- Receptors, Serotonin -- drug effects
- Serotonin Antagonists -- pharmacology
- Serotonin Receptor Agonists -- pharmacology
- Signal Transduction -- drug effects
- Subcellular Fractions -- drug effects
- Tritium -- pharmacokinetics
- Type C Phospholipases -- deficiency
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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