Regulation of type-II collagen gene expression during human chondrocyte de-differentiation and recovery of chondrocyte-specific phenotype in culture involves Sry-type high-mobility-group box (SOX) transcription factors. [electronic resource]
Producer: 20020110Description: 461-70 p. digitalISSN:- 0264-6021
- Animals
- Base Sequence
- Cattle
- Cell Culture Techniques -- methods
- Cell Differentiation -- genetics
- Cells, Cultured
- Chondrocytes -- cytology
- Collagen Type II -- biosynthesis
- DNA-Binding Proteins -- metabolism
- Enhancer Elements, Genetic
- Fetus
- Gene Expression Profiling
- Gene Expression Regulation, Developmental
- High Mobility Group Proteins -- metabolism
- Humans
- Molecular Sequence Data
- Nuclear Proteins -- metabolism
- Phenotype
- Promoter Regions, Genetic
- Protein Binding -- genetics
- SOX9 Transcription Factor
- SOXD Transcription Factors
- Sex Determination Processes
- Sex-Determining Region Y Protein
- Transcription Factors -- metabolism
- Up-Regulation -- genetics
- Y Chromosome -- genetics
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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