Altering the GTP binding site of the DNA/RNA-binding protein, Translin/TB-RBP, decreases RNA binding and may create a dominant negative phenotype. [electronic resource]
Producer: 20011204Description: 4433-40 p. digitalISSN:- 1362-4962
- 3T3 Cells
- Allosteric Regulation
- Allosteric Site
- Amino Acid Sequence
- Animals
- Carrier Proteins -- metabolism
- Cell Death
- DNA -- genetics
- DNA-Binding Proteins -- chemistry
- Dimerization
- Genes, Dominant -- genetics
- Guanosine 5'-O-(3-Thiotriphosphate) -- metabolism
- Guanosine Diphosphate -- metabolism
- Guanosine Triphosphate -- metabolism
- Humans
- Male
- Mice
- Mutation -- genetics
- Nuclear Proteins -- metabolism
- Phenotype
- Protein Binding
- Protein Structure, Tertiary
- RNA -- genetics
- RNA-Binding Proteins -- chemistry
- Testis -- metabolism
- Two-Hybrid System Techniques
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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