A novel tetrameric venom protein, agglucetin from Agkistrodon acutus, acts as a glycoprotein Ib agonist. [electronic resource]
Producer: 20020502Description: 1077-86 p. digitalISSN:- 0340-6245
- Agkistrodon -- metabolism
- Alprostadil -- pharmacology
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal -- immunology
- Binding, Competitive
- Blood Platelets -- drug effects
- Calcium Signaling -- drug effects
- Chelating Agents -- pharmacology
- Crotalid Venoms -- chemistry
- Dose-Response Relationship, Drug
- Edetic Acid -- pharmacology
- Epitopes -- immunology
- Fibrinolytic Agents -- isolation & purification
- Heparin -- pharmacology
- Hirudins -- pharmacology
- Humans
- Indomethacin -- pharmacology
- Intercellular Signaling Peptides and Proteins
- Molecular Sequence Data
- Molecular Weight
- Peptides -- pharmacology
- Platelet Aggregation -- drug effects
- Platelet Glycoprotein GPIb-IX Complex -- antagonists & inhibitors
- Prostaglandin Antagonists -- pharmacology
- Protein Conformation
- Protein Subunits
- Sequence Alignment
- Sequence Homology, Amino Acid
- Spectrometry, Mass, Electrospray Ionization
- Thromboxane B2 -- biosynthesis
- von Willebrand Factor -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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