Oxidation of beta2-glycoprotein I (beta2GPI) by the hydroxyl radical alters phospholipid binding and modulates recognition by anti-beta2GPI autoantibodies. [electronic resource]
Producer: 20020502Description: 1070-6 p. digitalISSN:- 0340-6245
- Animals
- Antibodies, Antiphospholipid -- immunology
- Antibody Affinity
- Antibody Specificity
- Antigen-Antibody Reactions
- Antiphospholipid Syndrome -- etiology
- Autoantibodies -- immunology
- Autoimmune Diseases -- immunology
- Cardiolipins -- immunology
- Cattle
- Dimerization
- Enzyme-Linked Immunosorbent Assay
- Epitopes -- immunology
- Free Radical Scavengers -- pharmacology
- Gamma Rays
- Glycoproteins -- chemistry
- Humans
- Hydroxyl Radical -- pharmacology
- Immunoglobulin G -- immunology
- Liposomes
- Lupus Erythematosus, Systemic -- complications
- Macromolecular Substances
- Mannitol -- pharmacology
- Oxidation-Reduction
- Phospholipids -- immunology
- Structure-Activity Relationship
- Thiourea -- pharmacology
- Thrombophilia -- immunology
- Tryptophan -- chemistry
- Water
- beta 2-Glycoprotein I
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Publication Type: Comparative Study; Journal Article
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