Gi- and Gs-coupled receptors up-regulate the cAMP cascade to modulate HCN2, but not HCN1 pacemaker channels. [electronic resource]
Producer: 20020221Description: 928-42 p. digitalISSN:- 0031-6768
- Adenine -- analogs & derivatives
- Animals
- Cyclic AMP -- metabolism
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Cyclic Nucleotide-Gated Cation Channels
- Electric Conductivity
- Enkephalin, Ala(2)-MePhe(4)-Gly(5)- -- pharmacology
- Female
- GTP-Binding Protein alpha Subunits, Gi-Go -- physiology
- GTP-Binding Protein alpha Subunits, Gs -- physiology
- Gene Expression
- Humans
- Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
- Ion Channels -- genetics
- Membrane Potentials
- Muscle Proteins
- Nerve Tissue Proteins
- Oocytes -- metabolism
- Potassium Channels
- Protein Kinase C -- metabolism
- Receptors, Opioid, mu -- physiology
- Receptors, Serotonin -- physiology
- Transfection
- Xenopus
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Publication Type: Journal Article
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