Isotype-switched immunoglobulin genes with a high load of somatic hypermutation and lack of ongoing mutational activity are prevalent in mediastinal B-cell lymphoma. [electronic resource]
Producer: 20011207Description: 2762-70 p. digitalISSN:- 0006-4971
- Adult
- Antibodies, Neoplasm -- analysis
- Base Sequence
- Clone Cells -- immunology
- Female
- Gene Expression Regulation
- Gene Rearrangement
- Humans
- Immunoglobulin Class Switching -- genetics
- Immunoglobulin G -- drug effects
- Immunoglobulin Heavy Chains -- genetics
- Immunoglobulin Variable Region -- genetics
- Lymphoma, B-Cell -- genetics
- Lymphoma, Large B-Cell, Diffuse -- genetics
- Male
- Mediastinal Neoplasms -- genetics
- Middle Aged
- Molecular Sequence Data
- Mutation
- RNA, Messenger -- analysis
- RNA, Neoplasm -- analysis
- Somatic Hypermutation, Immunoglobulin -- genetics
- Tumor Cells, Cultured
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Publication Type: Journal Article
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