Sphingosine 1-phosphate activates nuclear factor-kappa B through Edg receptors. Activation through Edg-3 and Edg-5, but not Edg-1, in human embryonic kidney 293 cells. [electronic resource]
Producer: 20020131Description: 48733-9 p. digitalISSN:- 0021-9258
- Calcium -- metabolism
- Calcium Signaling -- physiology
- Carbachol -- pharmacology
- Cell Line
- Cholinergic Agonists -- pharmacology
- DNA-Binding Proteins -- metabolism
- Enzyme Inhibitors -- pharmacology
- Genes, Reporter
- Heterotrimeric GTP-Binding Proteins -- metabolism
- Humans
- I-kappa B Proteins
- Immediate-Early Proteins -- metabolism
- Lysophospholipids
- NF-KappaB Inhibitor alpha
- NF-kappa B -- antagonists & inhibitors
- Protein Kinase C -- metabolism
- Receptor, Muscarinic M3
- Receptors, Cell Surface -- metabolism
- Receptors, G-Protein-Coupled
- Receptors, Lysophospholipid
- Receptors, Muscarinic -- metabolism
- Sphingosine -- analogs & derivatives
- rho GTP-Binding Proteins -- metabolism
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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