Design, synthesis, and biological evaluation of novel nucleoside and nucleotide analogues as agents against DNA viruses and/or retroviruses. [electronic resource]
Producer: 20011204Description: 3710-20 p. digitalISSN:- 0022-2623
- Adenine -- analogs & derivatives
- Adenine Nucleotides -- chemical synthesis
- Adenosine Deaminase Inhibitors
- Animals
- Antineoplastic Agents -- chemical synthesis
- Antiviral Agents -- chemical synthesis
- Cell Line
- Chlorocebus aethiops
- DNA Viruses -- drug effects
- Drug Design
- Enzyme Inhibitors -- chemical synthesis
- Lethal Dose 50
- Leukemia, Experimental -- drug therapy
- Mice
- Nucleosides -- chemical synthesis
- Nucleotides -- chemical synthesis
- Phosphoric Diester Hydrolases -- chemistry
- Phosphorylation
- Retroviridae -- drug effects
- Retroviridae Infections -- drug therapy
- Simplexvirus -- enzymology
- Snake Venoms -- enzymology
- Spleen -- enzymology
- Thymidine Kinase -- antagonists & inhibitors
- Tumor Virus Infections -- drug therapy
- Vero Cells
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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