DNA immunization of HLA transgenic mice with a plasmid expressing mycobacterial heat shock protein 65 results in HLA class I- and II-restricted T cell responses that can be augmented by cytokines. [electronic resource]
Producer: 20011204Description: 1797-804 p. digitalISSN:- 1043-0342
- Animals
- Bacterial Proteins
- COS Cells
- Cell Division
- Chaperonin 60
- Chaperonins -- genetics
- Cytokines -- metabolism
- Epitopes -- chemistry
- Genes, MHC Class I -- genetics
- Genes, MHC Class II -- genetics
- HLA-A2 Antigen -- metabolism
- Humans
- Interferon-gamma -- metabolism
- Jurkat Cells
- Mice
- Mice, Transgenic
- Mycobacterium -- metabolism
- Peptides -- chemistry
- Plasmids -- metabolism
- Protein Binding
- T-Lymphocytes -- metabolism
- Transfection
- Vaccines, DNA
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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