Caspase-3 cleaves Apaf-1 into an approximately 30 kDa fragment that associates with an inappropriately oligomerized and biologically inactive approximately 1.4 MDa apoptosome complex. [electronic resource]
Producer: 20011204Description: 425-33 p. digitalISSN:- 1350-9047
- Amino Acid Sequence
- Antibodies -- immunology
- Apoptosis
- Apoptotic Protease-Activating Factor 1
- Caspase 3
- Caspase 7
- Caspases -- genetics
- Cell Line
- Deoxyadenine Nucleotides -- pharmacology
- Humans
- Macromolecular Substances
- Molecular Weight
- Protein Conformation
- Proteins -- chemistry
- Recombinant Proteins -- pharmacology
- X-Linked Inhibitor of Apoptosis Protein
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Publication Type: Journal Article
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