Activation of caspases occurs downstream from radical oxygen species production, Bcl-xL down-regulation, and early cytochrome C release in apoptosis induced by transforming growth factor beta in rat fetal hepatocytes. [electronic resource]
Producer: 20010920Description: 548-56 p. digitalISSN:- 0270-9139
- Animals
- Apoptosis -- physiology
- Caspases -- physiology
- Cells, Cultured
- Cytochrome c Group -- metabolism
- Down-Regulation -- physiology
- Enzyme Activation
- Fetus
- Hepatocytes -- drug effects
- Humans
- Mitochondria, Liver -- physiology
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Rats
- Rats, Wistar
- Reactive Oxygen Species -- metabolism
- Recombinant Proteins -- pharmacology
- Time Factors
- Transforming Growth Factor beta -- pharmacology
- bcl-X Protein
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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