Selective and rapid liquid chromatography-mass spectrometry method for the quantification of rofecoxib in pharmacokinetic studies with humans. [electronic resource]
Producer: 20020205Description: 83-90 p. digitalISSN:- 1387-2273
- Adult
- Area Under Curve
- Atmospheric Pressure
- Chromatography, High Pressure Liquid -- methods
- Cyclooxygenase 2
- Cyclooxygenase 2 Inhibitors
- Cyclooxygenase Inhibitors -- blood
- Female
- Humans
- Isoenzymes -- drug effects
- Lactones -- blood
- Male
- Mass Spectrometry -- methods
- Membrane Proteins
- Prostaglandin-Endoperoxide Synthases -- drug effects
- Reference Standards
- Reproducibility of Results
- Sensitivity and Specificity
- Sulfones
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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