Induction of hepatic microsomal drug-metabolizing enzymes by inhibitors of 5-lipoxygenase (5-LO): studies in rats and 5-LO knockout mice. [electronic resource]
Producer: 20011025Description: 15-21 p. digitalISSN:- 1096-6080
- Animals
- Arachidonate 5-Lipoxygenase -- deficiency
- Cytochrome P-450 Enzyme System -- biosynthesis
- Dose-Response Relationship, Drug
- Enzyme Induction
- Hydroxyurea -- analogs & derivatives
- Lipoxygenase Inhibitors -- pharmacology
- Liver -- drug effects
- Male
- Mice
- Mice, Inbred DBA
- Mice, Knockout
- Microsomes, Liver -- drug effects
- NADH Dehydrogenase -- biosynthesis
- Organ Size -- drug effects
- Pyrans -- pharmacology
- Quinolones -- pharmacology
- Rats
- Rats, Sprague-Dawley
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Publication Type: Journal Article
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