Role for endothelin-1-induced superoxide and peroxynitrite production in rebound pulmonary hypertension associated with inhaled nitric oxide therapy. [electronic resource]
Producer: 20010830Description: 357-64 p. digitalISSN:- 1524-4571
- Administration, Inhalation
- Animals
- Blotting, Western
- Cells, Cultured
- Dioxoles -- pharmacology
- Disease Models, Animal
- Endothelin Receptor Antagonists
- Endothelin-1 -- metabolism
- Enzyme Activation -- drug effects
- Humans
- Hypertension, Pulmonary -- chemically induced
- Lung -- chemistry
- Microscopy, Fluorescence
- Muscle, Smooth, Vascular -- cytology
- Nitrates -- chemistry
- Nitric Oxide -- administration & dosage
- Nitric Oxide Donors -- pharmacology
- Nitric Oxide Synthase -- chemistry
- Nitric Oxide Synthase Type III
- Pulmonary Artery -- cytology
- Receptor, Endothelin A
- Secondary Prevention
- Sheep
- Superoxides -- metabolism
- Tyrosine -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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