STAT3 activation is required for Asp(816) mutant c-Kit induced tumorigenicity. [electronic resource]
Producer: 20010906Description: 4528-36 p. digitalISSN:- 0950-9232
- Amino Acid Substitution
- Animals
- Cell Division -- drug effects
- Cell Line, Transformed -- drug effects
- Cell Transformation, Neoplastic -- genetics
- Cells, Cultured
- Codon -- genetics
- DNA-Binding Proteins -- physiology
- Dimerization
- Humans
- Kidney -- cytology
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Mutation, Missense
- Neoplasm Transplantation
- Oncogenes
- Proto-Oncogene Proteins c-kit -- chemistry
- Recombinant Proteins -- pharmacology
- STAT1 Transcription Factor
- STAT3 Transcription Factor
- Signal Transduction
- Stem Cell Factor -- pharmacology
- Trans-Activators -- physiology
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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