Potent dibasic GPIIb/IIIa antagonists with reduced prolongation of bleeding time: synthesis and pharmacological evaluation of 2-oxopiperazine derivatives. [electronic resource]
Producer: 20010802Description: 2438-50 p. digitalISSN:- 0022-2623
- Adenosine Diphosphate -- pharmacology
- Animals
- Bleeding Time
- Carotid Artery Thrombosis -- drug therapy
- Catheterization
- Drug Evaluation, Preclinical
- Fibrinolytic Agents -- chemical synthesis
- Guanidines -- chemical synthesis
- Guinea Pigs
- Humans
- In Vitro Techniques
- Macaca fascicularis
- Male
- Piperazines -- chemical synthesis
- Platelet Aggregation Inhibitors -- chemical synthesis
- Platelet Glycoprotein GPIIb-IIIa Complex -- antagonists & inhibitors
- Structure-Activity Relationship
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Publication Type: Journal Article
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