Two splice variants of protein kinase B gamma have different regulatory capacity depending on the presence or absence of the regulatory phosphorylation site serine 472 in the carboxyl-terminal hydrophobic domain. [electronic resource]
Producer: 20010913Description: 29550-8 p. digitalISSN:- 0021-9258
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Brain -- enzymology
- Cloning, Molecular
- Conserved Sequence
- Embryo, Mammalian
- Enzyme Activation
- Exons
- Genetic Variation
- Humans
- Kinetics
- Male
- Mice
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Oligopeptides -- chemistry
- Oncogene Proteins -- chemistry
- Organ Specificity
- Phosphorylation
- Protein Serine-Threonine Kinases -- chemistry
- Proto-Oncogene Proteins c-akt
- Rats
- Recombinant Proteins -- chemistry
- Reverse Transcriptase Polymerase Chain Reaction
- Sequence Alignment
- Sequence Homology, Amino Acid
- Serine
- Substrate Specificity
- Transcription, Genetic
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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